Around 8:30 a.m. on Tuesday morning, Guelph Police responded to a crash in the area of Gosling Gardens and Doyle Drive.
A Honda Accord driven by a 56 year old Guelph man, and a Toyota Camry driven by a 48 year old Niagara Falls man collided.
Both drivers and a passenger from the Honda were taken to hospital by ambulance.
The drivers were released with minor injuries, but the passenger, who is pregnant, is being held for observation.
As a result of the crash, Gosling Gardens was closed from Clair Rd and Clairfields Drive for around 3 hours.
Anyone who may have witnessed the crash are asked to contact Guelph Police.